Absolutely it matters, Federal cases are not remotely like a state criminal case. You need a lawyer who is fully experienced in dealing with the Federal government and its prosecutors. The average state court lawyer is not equipped to handle the complexity which exists in Federal prosecution. Federal criminal defense is much like a specialty in that it requires detailed knowledge of the Federal statutes, rules, and practices. The time frames in Federal court are different than state court and the stakes are generally much higher. Your lawyer should be able to explain in detail the overall process and how Federal proceedings specifically will be conducted. If your lawyer cannot do this off the top of his head, find one who can.